Using Alpha-Lipoic Acid for Gout Relief and Prevention

Alpha-lipoic acid is an antioxidant that can be found in yeast, liver, kidney, spinach, potatoes and broccoli. It is also possible to produce alpha-lipoic acid in a laboratory setting for medicinal uses, making it easily available for supplemental use. Alpha-lipoic acid’s activities have been shown to prevent cell damage in the body, restore vitamin levels such as vitamin E and C, aid in the breakdown of carbohydrates and providing energy for the organs in the body, and finally has been helpful in treating and preventing liver disease.

Alpha-Lipoic Acid for Gout Relief and Prevention

Alpha-Lipoic acid’s significant involvement in energy metabolism – which is the breakdown to carbohydrates to create energy for the body’s organs – ensures that organs such as your liver and kidneys are supplemented with enough fuel to function efficiently. Liver and kidney health are essential for gout relief and prevention because the two organs are directly involved in the filtration and excretion of uric acid in the body. When uric acid is present in high levels, the organs have to work harder and deplete more energy to push the waste product out. Alpha-lipoic acid helps to efficiently breakdown the carbohydrates in your body to provide your liver and kidneys with the energy it needs to work through a flare up.

Its potent anti-oxidant properties make it a critical partner for vitamins such as vitamin E and vitamin C, restoring the maintaining appropriate amounts of these vitamins to help in energy production. Restoration of vitamin C is critical as evidence has displayed that vitamin C plays a significant role in lowering uric acid levels.

Finally Alpha-lipoic acid provides anti-inflammatory relief which can help with the pain caused during a gout attack and can also help prevent uric acid crystals from inducing inflammation on the joint. It should be noted that alpha-lipoic acid is most potent when in combination with other anti-inflammatory compounds such as bromelain.

Research Supporting Alpha-Lipoic Acid and Gout Relief and Prevention

A study conducted on rats with kidney injuries observed the effects of alpha-lipoic acid and oxidative damage incurred on the kidneys. The results confirmed that alpha-lipoic acid was successful in partial damage prevention thanks to its anti-inflammatory and antioxidant properties. Another study evaluated the efficacy of a combination treatment of N-acetyl cysteine, alpha-lipoic acid and bromelain and found that the combination ingredients were highly successful in providing anti-inflammatory relief.

Alpha-Lipoic Acid Sources

Alpha-lipoic acid can be found in meat sources such as liver and kidneys. Unfortunately, these sources are typically high in proteins and are therefore not a good option for gout sufferers. The compound can also be found in vegetables such as spinach, broccoli and potatoes, but are typically in very low and insignificant quantities. A popular source of alpha-lipoic acid are supplements, which are derived from laboratory created alpha-lipoic acid that are served in dosages that can make a significant impact.

Alpha-Lipoic Acid Supplement Variations

Alpha-lipoic acid is primarily available in powder form, typically encapsulated and served in recommended dosages. There are a variety of capsule supplements available that differ in dosage amounts.

How to Use Alpha-Lipoic Acid for Gout Relief and Prevention

Obtaining alpha-lipoic acid naturally through preferred food sources is the best primary method for gout relief and prevention. Not only do these alpha-lipoic acid rich foods provide you with gout prevention benefits, but they are also acceptable forms of food for healthy eating habits. Typically however, alpha-lipoic acid is available through supplement form and is best to be taken in a combination supplement. A supplement that pair alpha-lipoic acid with bromelain or other enhancing ingredients can help increase the effects and activity of alpha-lipoic acid, thus making it more effective in your body. Alpha-lipoic acid should be taken in a range of 300-600 mg dosages to obtain the best results.


Alpha-lipoic acid is considered safe for most adults when taken orally, however like all drugs and medications it can cause side-effects. It can possible cause rashes, an upset stomach or nausea. Not enough is known about the supplement and its effects on pregnancy and breast-feeding and it is recommended you avoid this substance under these conditions. Alpha-lipoic acid can decrease blood sugar levels, therefore individuals with diabetes should monitor their blood levels if taking this supplement.

Side Effects

Alpha-lipoic acid that is taken orally may cause skin rashes, stomach and bowel discomfort or nausea. The ingredient is not recommended for women who are breastfeeding or pregnant as not enough is known of the drug’s effects in these circumstances. Individuals with diabetes should monitor their blood levels as alpha-lipoic acid can decrease blood sugar levels.

Interactions with other Medications

Alpha-lipoic acid can interact with the following medications:

  • Chemotherapy. Antioxidants pose a concern in that they might decrease the effectiveness of cancer medications. Speak to your doctor if you are on cancer medication or receiving chemotherapy before taking alpha-lipoic acid.
  • Antidiabetes drugs. Alpha-lipoic acid may lower blood sugar levels which can increase the effectiveness of diabetes medications. Monitor your blood sugar levels closely if taking alpha-lipoic acid.

Frequently Asked Questions

Can Alpha-lipoic acid cause gout?

Alpha-lipoic acid can play a critical role in preventing and proving relief for gout. Its combination activity that includes, providing energy for essential organs (such as the kidneys and liver), restoring and maintaining vitamin C and E levels and its anti-inflammatory properties make it an ideal dietary ingredient in gout prevention and relief.